Even the author admitted it. The media and medical establishment did not read the study carefully. They seize on anything that supports the narrative and fail to look at the study critically.
I just got off the phone with Pierre Kory. He just got back into the country and on Monday, April 4, he will be writing an article on his Substack on the ivermectin arm of the Together Trial. Let’s just say Pierre is not a happy camper. I haven’t seen him this upset ever.
Here is what Peter McCullough wrote: “Dose too small and for too few days too late in course of illness. Despite all of these deficiencies, this small underpowered trial still showed a signal of benefit and presumed acceptable safety. Another paper supporting our use of IVM.”
I agree. Here’s my take on this.
Ivermectin works and this study didn’t prove otherwise
The most important thing is this: The evidence, including this study, consistently shows that ivermectin works against COVID. In one group, as I will explain below (and I’m sure Pierre will explain in more detail), there was a 50% reduction in hospitalization. That’s big.
However, the media (including Alex Berenson) don’t want to look like they were wrong so they simply misinterpret the study results and hope you won’t read the study yourself.
What the study actually showed
Disease, timing, dose, duration, and statistical power are all important to talk about whenever you talk about the results of any drug trial. There are other secondary factors regarding gaming, tampering, quality control, etc. that are important and are always overlooked. Let’s just address the biggest factors.
What the study showed is this:
For the P.1 variant of the virus, giving a low dose of ivermectin (0.4mg/kg) for just 3 days starting up to 8 days days after first symptoms as a monotherapy (i.e., with no other drugs) results in a small effect that requires more patients in your study than you originally thought to prove it is statistically significant.
That doesn’t mean the drug didn’t work. It just means it was underpowered for the variant it was given against as a monotherapy for just 3 days.
It’s pretty clear that had the study enrolled more patients, ivermectin would have “worked” and the results would have been statistically significant. The author admits this….